The choice of the treatment to perform with sodium bicarbonate depends on two factors: the size of the mass and the depth of infiltration in the intestinal wall.
In cases where the neoplasia – regardless of its shape – is all inside the intestinal lumen, the most effective method of attack is colonoscopy, through which it is possible to administer 150-200 grams of sodium bicarbonate in two liters of lukewarm water, going as far as the ileum-caecal valve.
Even when the masses regress conspicuously within a few days it is best to program from seven to nine sessions for a period of three to four weeks, keeping in mind that the first ones must be close together to have an immediate effect, and that the last ones are for the purpose of consolidation.
The possible crossing beyond the intestinal wall, or the simultaneous presence of a hepatic metastasis imposes a specific therapy for these organs as well.
Temporary episodes of diarrhea can take place during or after each session with bicarbonate salts, but this is not a reason to interrupt the therapy; at most, it may be appropriate to pause for some days.
Under a certain size, that is if the tumor has not completely invaded the intestinal lumen to the point of sub-occlusion or occlusion, the endoscopic treatment turns out to be very efficacious for obtaining regression of the masses.
Where, instead, there is an extreme situation or the simultaneous presence of another synchronous tumor, that is, existing in other sections of the intestine, and where it would be very difficult to reach after passing the first mass, then surgical intervention is indicated in such cases, as it saves the performance of the canal down to the anus.
This is possible through terminal or lateral anastomosis of the resected stumps, both treated later in the surgical theatre and through post-surgical draining with local and regional administration of sodium bicarbonate capable of preventing the formation of possible local or hepatic relapses.
When tissues are more vulnerable in the cicatricial points where reactivity equals zero, or at the hepatic level because of the toxic effects of the anesthesia, treatment with bicarbonate prevents that fungin regermination that most of the time causes a return of the disease and is impossible to cure. The indications for prevention in this case are the same as those for the therapy of peritoneal carcinosis.