Peritoneal carcinomatosis

Peritoneal carcinosis in adenocarcinoma of endometrium

A 62-year-old patient undergoes surgery in December 1998 for endometrial adenocarcinoma, followed by successive cycles of radiotherapy and anti-hormone therapy. Following the thickening of the peritoneum and the growth of several lymph nodes due to carcinosis, the ovarian CA antigen increases progressively notwithstanding treatment with Tamoxiphen up to a value of 125 UI/ml (v.n. 0-35) on June 3, 2002.

From the clinical point of view, the patient’s condition decayed with the presence of exhaustion, general swelling, intestinal meteorism, irregularity of evacuation, steady feeling of heaviness and blood pressure instability. In July and October 2002, an endoperitoneal catheter is inserted through which, in cycles, sodium bicarbonate is administered at a 5% solution (400-500 cc), alternating with intravenous cycles.

The clinical condition of the patient constantly improves up to a normal condition of health. The ovarian CA antigen progressively decreases and in March 2003 it reaches a value of 49.70 UI/ml, a value that is also confirmed in June, 2003. A last CAT scan performed in June 2003 confirms the regression of the peritoneal carcinosis and a stabilisation of the size of the lymph nodes when compared to the preceding year.

Translation of document:  I was operated on December 18 1998 for endometrial adenocarcinoma. In February-March 1999 I underwent 29 sessions of radiotherapy. The routine checks performed in the last months of 2000 have indicated alterations to the ovarian Ag Ca. The CAT scan highlighted the presence of tumoral cells in the lymph nodes. The oncological department initiated treatment with Tamoxiphen which, however, I abandoned after awhile as I chose to undergo Dr. Tullio Simoncini’s therapy.

On July 20, 2002, the radiologist Dr…. installed an endoperitoneal transdermal catheter and I started the sodium bicarbonate 5% solution therapy. The CAT check performed on September 6 has highlighted a stabilisation when compared with the previous scan of May 2002, while the previous thickenings likely due to peritoneal carcinosis are no longer visible.

I would like to highlight that when I was telling Dr. Simoncini that I was feeling good his answer was : ‘May God help us, sister: I don’t say anything, for only the checkups can say something; I can ensure nothing, we shall see.’ On October 5, Dr. Simoncini updated me on the situation. The radiologist, Dr…., once he had examined the check-up CAT, stated that since an internal abscess had formed, this had prevented the outcome they had hoped for. He therefore suggested the installation of a new catheter, which was done on October 16, 2002 by Dr…..

From this moment on, I continue with the sodium bicarbonate therapy on a regular basis. The various hematochemical checkups give better values each time; starting from the ovarian 125 Ag Ca of June 2002 up to the present 49.70 of March 7, 2003. Furthermore, the CAT performed in December 2002 shows that the situation of May 2002 has not changed. It is to be highlighted that, from the clinical point of view, my condition has steadily improved.  The intestinal and hepatic suffering is gone, the blood pressure has regularised and the swelling of the heels is gone along with the general swelling.

I am aware that much is still to be done to reach the security of the complete regression of the disease, as I am often reminded by Dr. Simoncini, who is always very conservative. At any rate, and given the results that have been reached, there is the hope that, working steadily, we can get to a final resolution of the disease.

I would like to formulate a wish: if Dr. Simoncini had the opportunity to work in his own clinic he could help many other people who are hit by cancer. I thank God for giving me new life and Dr. Simoncini, who has been His instrument to help me.


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