There are a large number of works that document the constant presence of the mycetes in the tissues of cancer patients, especially in terminal patients.
In recent years, we have observed a crescendo of voices addressing this terrible fungus to the point of defining it as ‘the most important and most urgent problem that oncology has to solve’.
The following figures concerning the coexistence of Candida and cancer have been collected by several authors:
- R.L. Hopfer: 79%
- U. Kaben: 80%
- W. T. Hughes: 91 %
- T.E. Kiehn: 97%
The percentages observed are truly impressive, especially when considering the difficulty of seeing Candida in the organic materials to be examined. This was also reported by R.S. Escuro, Z. O. Karaev, and T.J. Walsh.
The positive results quoted allow us to confirm that Candida is always present in the tissues of cancer patients. Not only that, but Candida species represent today, according to several scholars, the first cause of morbidity and mortality in patients affected by neoplasias of the hemolinphopoietic system.
O. Uzun even analyzed all data from 1974 to 1999 concerning the presence of candidosis in patients and the prognostic factors including predictable elements of mortality and came to the conclusion that the global rate of mortality in cancer patients varies between 33% and 75% and that this is independent of the type of infecting Candida.
The phenomenon is usually interpreted as a consequence of the weakening and of the exhaustion of the organism because of neoplastic lesions. Conversely, we have to believe that the aggression of Candida takes place in the carcinogenic sense after the superficial pathogenic phases – that is, the classic epithelial candidosis - in several stages:
- rooting in the deep connective tissue (in the various organs)
- expansion with evoking of an organic reaction that attempts to encyst the fungin colonies, with the outcome being the formation of neoplasias
- growth both in the surrounding tissue and remotely (metastasis).
- progressive exhaustion of the organism with consequential global organism invasion. This is the stage that is most commonly observed and that is considered ‘opportunistic’
In summary, Candida is not a post hoc but an ante hoc cause.