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sodium bicarbonate case report by Ricardo Luiz Capuano

simple tubular adenocarcinoma - stage 3

 

Summary:
Mammary tumors are very common in cats and dogs. There is a large range of histological types which attack dogs, but most of the tumors are benign. Around 50% of the mammary tumors are malignant. Referring to cats, around 80% of the tumors are malignant and highly aggressive. Among the most aggressive types of tumors, adenocarcinoma is one of the most common.

Adenocarcinoma is a type of cancer (malignant neoplasia) which is originated from a glandular tissue, in this case, the mammary gland. In general, adenocarcinomas are difficult to be removed surgically; they grow very fast and are very aggressive. Adenocarcinomas also cause metastasis in non-glandular tissues, constituting a type of cancer with unfavorable prognostic, independent from the site.

The histopathological classification of malignancy proposed by the World Health Organization (WHO), in 2005, based on the degree of cellular differentiation, classified this malignant neoplasia into three categories, considering degree III as the most malignant. This evaluation takes into consideration, the amount of altered cells and the severity of the alterations.

It was reported the attendance and follow-up of the feline animal, called Kim, 14 years old, 3,2 kg, with recurrent mammary adenocarcinoma, degree III. We have decided to treat the animal, by infiltrating shots around the tumor with sodium bicarbonate, adapting the animal to the proposed treatment by Dr. Tullio Simoncini, for humans. This type of treatment was selected, due to continuous recurrence, considering that the animal had undergone surgeries for tumor removal in another clinic, in 2006 and 2011, May 2012 and November 2012. From November 2012 to January 2013, there was a tumor growth, which started from 0 and reached 10cm length, 9cm width and 2cm height, in two months. Employing the above treatment, the tumor presented a reduction.

According to the evolution of the mammary tumor, it would be expected that in two following months (without treatment), it would reach 20cm x 18 cm. When working with living organisms, there are several variants which cannot be calculated, but anyway, in practically all the situations, a recurrent tumor, so aggressive as the type presented by the patient, should keep on growing.

In opposition to the normal sequence of the tumor development, it was observed that it stopped growing and reduced its size and its final measures were 5,5cm X 7,4cm X1,5 cm, respectively. There was a reduction of approximately 30% in the width, 25% in the length and thickness. The outcomes, even considering that the animal died, due to alterations caused by metastasis in the region of the intestines, the experiment was very important and additional studies are necessary.

Case report written by Veterinarian doctor Ricardo Luiz Capuano - Brazil

 

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